On June 1, 2023, China's Ministry of Science and Technology ("MOST") officially released the Implementation Rules for the Regulation of Human Genetic Resources Administration ("Implementation Rules"), which will come into effect on July 1, 2023. Since the release of the Rules for Implementation of the Regulations on Administration of Human Genetic Resources (Draft for Comments) in March 2022 by MOST ("Draft Rules"; for reference, please refer to Han Kun • Perspective Highlights on the Draft HGR Regulations Implementation Rules), the industry has been eagerly awaiting the finalization of the policies outlined in the Implementation Rules. We closely followed the updates and noticed that some changes in the Implementation Rules have already been reflected in the regulatory practice. The long-awaited release of the Implementation Rules marks a new stage in China's regulation of human genetic resources.